docTLDR

ChatGPT is rapidly entering clinical settings, offering instant medical information, patient triage, and even diagnostic suggestions. While it can streamline workflows and enhance patient education, experts warn that its lack of clinical judgment and risk of hallucinations mean it must not replace physician expertise. Regulatory and ethical frameworks are urgently needed as AI's clinical footprint expands.

Over two weeks after the NEET PG 2025 exam, the National Board of Examinations in Medical Sciences (NBEMS) has yet to announce results, causing widespread anxiety among candidates. Aspirants have taken to social media to express frustration and seek official updates. While NBEMS is expected to release results by September 3, 2025, the lack of communication has intensified calls for transparency and timely information.

The University Grants Commission has banned online and distance learning for healthcare and allied subjects, including psychology, microbiology, and biotechnology, effective this academic year. All prior approvals are revoked, and new admissions are barred. The move aims to uphold quality standards in disciplines requiring hands-on training, directly impacting medical colleges and thousands of students.

India's PHCs have improved significantly, but public perception lags behind. Many facilities now deliver quality care, yet negative stereotypes persist. Doctors in PHCs should note the importance of positive engagement and storytelling to boost morale and public trust, which can drive better patient outcomes and system utilization.

The Indian government is actively considering reducing or scrapping GST on health and term insurance, which could make policies significantly more affordable for families and first-time buyers. This move is expected to increase insurance penetration, especially among low- and middle-income groups, and help advance universal health coverage. Doctors should anticipate a surge in insured patients and broader access to care.

The Technology Development Board has partnered with Primary Healthtech Pvt. Ltd. to scale up an IoT-enabled, AI-powered point-of-care blood testing device. The portable Mobilab analyzer, already trialed on 10,000 patients and CDSCO-approved, can test over 25 parameters and aims to bridge diagnostic gaps in rural and underserved regions, supporting Atmanirbhar Bharat.

The FDA has granted accelerated approval to Wegovy (semaglutide) for adults with metabolic dysfunction-associated steatohepatitis (MASH) and moderate to advanced liver fibrosis, but not cirrhosis. Approval is based on the ESSENCE trial, where Wegovy showed significant improvement in liver fibrosis and steatohepatitis compared to placebo. This marks the first GLP-1 agonist approved for MASH with fibrosis, expanding treatment options for this serious liver disease.

A government bus suffered brake failure near Chengalpattu, veering into pedestrians and colliding with a private bus. Dr S Manikumar, a paediatrician at Chengalpattu Government Medical College Hospital, died instantly, while Dr Praveen Kumar and 17 others sustained serious injuries. The Health Minister visited the victims, and police have launched an investigation into the incident.

A large UK Biobank genetic analysis found no evidence that higher BMI or body fat protects against cardiovascular mortality in patients with CVD. While observational studies suggested overweight or mild obesity may lower mortality, Mendelian randomization using polygenic risk scores for BMI, body fat percentage, and central obesity showed increased fat is linked to higher cardiovascular death risk. The study highlights that the obesity paradox is likely due to confounding, and targeting fat r...

The US FDA has approved Tonmya (cyclobenzaprine HCl sublingual tablet), marking the first new fibromyalgia therapy in over 15 years. Tonmya is a non-opioid, rapidly absorbed, once-daily bedtime treatment targeting pain and nonrestorative sleep in adults. Phase 3 trials showed significant pain reduction and improved sleep quality, with the most common side effect being temporary mouth numbness. Tonmya is expected to be available in late 2025.

A large retrospective cohort study found no association between low-dose oral minoxidil and tachycardia in patients with non-scarring alopecia. This finding supports the cardiovascular safety of low-dose oral minoxidil for hair loss, addressing concerns about potential heart rate increases and expanding safe prescribing options for dermatologists.

India is moving to reform its regulatory landscape with AI-powered approvals, adaptive trials, and a single-window digital platform. These changes aim to accelerate device and drug innovation, improve market access for startups, and help Indian clinicians access cutting-edge therapies faster—critical as China races ahead in biotech innovation.

Girls experiencing puberty before age 11 or childbirth before 21 face double the risk of type 2 diabetes, heart failure, and obesity, and quadruple the risk of severe metabolic disorders. Later puberty and childbirth are genetically linked to longer lifespan, slower aging, and reduced risk of age-related diseases. The study identifies 126 genetic markers mediating these effects, highlighting the need to consider reproductive history in broader health assessments.

India's suspension of refurbished medical device imports is straining healthcare delivery in tier 2–4 cities and rural areas, warns the Medical Technology Association of India (MTaI). The group urges interim imports with regulatory approvals, citing a 10% market share for pre-owned devices and risks to provider capacity and jobs. Inclusion in the ERSO repair initiative could boost local repair expertise and access.

A systematic review published in Nutrients highlights naringin, a citrus flavonoid, for its potent antioxidant and anti-inflammatory effects on cardiovascular health. Naringin improved cardiac function and reduced myocardial damage in animal models, acting via PI3K/Akt and Nrf2/GPX4 pathways. Despite promising preclinical results, its low oral bioavailability limits clinical translation, prompting research into advanced delivery systems like liposomal encapsulation.